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Microarray Analysis of Differentially Expressed Genes Between Diabetes vs Healthy

Allam Appa Rao, Shyambabu M, Srinubabu Gedela*

*Corresponding author: Dr.Srinubabu Gedela,
Phone: +91-891-2844204,
Fax:     +91-891-2747969,
E-mail: srinubabuau6@gmail.com
Received April 20, 2008; Accepted May 15, 2008; Published May 25, 2008
Citation:  Allam AR, Shyambabu M, Srinubabu G (2008) Microarray Analysis of Differentially Expressed Genes Between Diabetes vs Healthy. J Proteomics Bioinform S1: S055-S084. doi:10.4172/jpb.s1000010
Copyright: ©2008 Allam AR, etal. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract

The expression profiling of diabetes vs. healthy is a method of identifying genes potentially involved in the pathogenic process. Microarray analysis enable one to determine the relative level of expression of practically all genes in a genome, allowing the prediction of cellular plans for protein synthesis to be established. We therefore took the approach of using microarray analysis to provide a list of genes that are differentially expressed between diabetes vs. healthy. Statistical methodologies are employed for interpretation of microarray results. The present chapter discusses the introduction to microarray analysis and statistical methods along with the application of our present study on differentially expressed genes of diabetes vs healthy.

 
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