23
2013
Neurology & Therapeutics
Neurology is a unique Medical Subject which deals with the disorders of the nervous system, and is studied as a specialized branch of science. Simply, neurology deals with the diagnosis and treatment of all categories of disease involving the central and peripheral nervous system; and the associated studies are reported in Open Access journals of OMICS publishing Group and the deliberations on those topics are held by eminent scientists and scholars at the OMICS Conference [...]
6
2013
Watertechnol2013 conference by OMICS Publishing Group
OMICS Publishing Group inviting everyone to International Exhibition and Conference on Water Technologies, Environmental Technologies, and Renewable Energy. This particular conference is going to hosted at the Bombay exhibition center for the duration of February 13-14, 2013 by. Water technologies for example filtration, ion exchange and ultra violet, all have their particular gains when attempting to engineer an all-inclusive water treatment methods. Every single day, huge numbers of people and large numbers of companies rely [...]
11
2012
Interview with Dr Srinubabu, MD of OMICS Group
OMICS Publishing and OMICS Group Conferences produce scientific journals, and organize scientific events respectively. Express Pharma interviewed the Director of OMICS Group, Dr. Srinubabu Gedela, on the scope of the conferences and the attendance of various delegates and its outcome with respect to the business scenario. He touched upon similar events addressing specialized areas within the concerned field. OMICS organizes the conferences throughout a calendar year in the US and India. Criteria for speaker selection [...]
12
2012
An Compressive Sensing Approach for Subtyping of Gliomaby
Gliomas are tumors originating from brain or spine and arise from glial cells. Gliomas are the most common type of primary brain tumors in adults. The classification of gliomas can be based on cell type, grade and location. For instance, gliomas can be classified into low-grade and high-grade determined by pathologic evaluation of the tumor. In this study Tang et al. we define the subtypes based on genetic and molecular signatures according to the reference. Combined analysis with different data typesof genome-wide [...]
12
2012
An Algorithm to Improve Disease Discrimination based on Gene Interactions
A strong statistical interactions is commonly associated with diseases. Disease classification could be significantly increased by our understanding of the gene interactions, especially when gene expression differs across different classes are not good enough, it is more important to take use of gene interactions for disease classification analyses. However, most gene selection algorithms in classification analyses merely focus on genes whose expression levels show differences across classes, and ignore the discriminatory information from gene interactions. [...]
12
2012
Waste to Watts:Improving Microbial Fuel Cells
This graphic shows the basic setup for a microbial fuel cell. An MFC consists of an anode, a cathode, a proton or cation exchange membrane and an electrical circuit. Anode respiring bacteria cling to the anode of the MFC. In the course of their metabolic activity, these bacteria strip electrons from organic waste. The electrons then flow through a circuit to the cathode, producing electricity in the process, in addition to CO2 and water. Hydroxide [...]
12
2012
Ions, Not Particles, Make Silver Toxic to Bacteria: Too Small a Dose May Enhance Microbes’ Immunity
Silver ions delivered by nanoparticles to bacteria promote lysis, the process by which cells break down and ultimately die, which makes silver nanoparticles a superior and widely used antibacterial agent. New research by Rice University found that silver ions, not the particles themselves, are toxic to bacteria. They also found that ligands in the vicinity of a bacteria can bind silver ions and prevent them from reaching their target. Rice University researchers have settled a [...]
11
2012
siRNA as novel anti-cancer therapeutic drugs
RNA interference (RNAi) has emerged as an attractive technology for silencing the expression of specific genes in human cells. In the physiological RNA interference pathway of gene silencing, double stranded RNAs are processed into small interfering RNAs (siRNA) by the RNase enzyme DICER. These siRNAs are incorporated into a RNA-induced silencing complex (RISC), that is capable of identifying and degrading mRNA that is complementary to the antisense strand of the siRNA thereby causing “gene silencing”. [...]
11
2012
Cancer Chemoprevention
Cancer is still a leading cause of deaths around the world, despite much significant advancement have been achieved in the cancer sciences. The cancers of lung and bronchus, and liver for male, and breast and lung ,and bronchus for female are estimated as the major reason for estimated deaths worldwide. Cancer can be induced by several endogenous and environmental causes as well as an adoption of cancer associated lifestyle choices including smoking, physical inactivity and [...]
11
2012
What are the Real Causes of Substrate Inhibition in the Glucuronidation Reaction?What are the Real Causes of Substrate Inhibition in the Glucuronidation Reaction?
UDP-Glucuronosyltransferases (UGTs) are a class of enzymes anchored in the membrane of endoplasmic reticulum. The UGT enzyme catalyzes glucuronidation, a major metabolic pathway in humans, by transferring a glucuronic acid from the cofactor UDPglucuronic acid to the substrate. In vitro characterization has revealed that many human UGT enzymes display substrate inhibition kinetics (i.e., inhibition of enzyme activity at high substrate concentrations). It is interesting to note that plant UDP-glucosyltransferases (using a similar catalytic mechanism as [...]
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