Journal of Molecular and Genetic Medicine is a peer reviewed scientific journal known for rapid dissemination of high-quality research. This Molecular and Genetic Medicine Journal with high impact factor offers an open access platform to the authors in academia and industry to publish their novel research. It serves the International Scientific Community with its standard research publications. Manuscripts in the following categories will be considered for publication: reviews and mini-reviews, research articles and short research reports, new methods and technologies, opinions on previously published literature and letters to the editor, meeting reports and commercial, patent and product news (inquiries to the Editor).
This journal is using Editorial Manager System for quality in peer-review process. Editorial Manager Systems is an online manuscript submission, review and tracking systems. Review processing is performed by the editorial board members of JMGM or outside experts; at least two independent reviewer’s approval followed by the editor is required for the acceptance of any citable manuscript. Authors may submit manuscripts and track their progress through the system, hopefully to publication. Reviewers can download manuscripts and submit their opinions to the editor. Editors can manage the whole submission/review/revise/publish process.
Medicinal genomics is the integration and application of genomic technologies allows biomedical researchers and clinicians to collect data from large study population and to understand disease and genetic bases of drug response. It includes genome structure, functional genomics, epigenomics, genome scale population genomics, systems analysis, pharmacogenomics and proteomics.
Genetic engineering is the genetic make-up of an organism’s genome using biotechnology tools and the one of the most powerful and promising application of the genetic engineering involves the treatment of genetic disorders like sickle cell anemia, Duchenne muscular dystrophy, cystis fibrosis, Tay-Sachs disease, Huntington’s chorea and Lesch-Nyhan syndrome. Now, medical Scientists can identify more than 3000 disorders happens because of the error in individuals DNA.
Pathology is a significant component of the medical sciences to understand the nature of the disease and a major field in diagnosis and modern medicine. It incorporates a wide range of medical practices and bioscience research to diagnose disease mostly by analysing cells, tissues and body fluids. Molecular medicine is an emerging area that aims to understand the molecular determinants of disease and health for the prevention, diagnosis and treatment using physical, chemical, biological and medical techniques.
Cellular medicine incorporates a wide range of biological processes from structure and function of biomolecules to cell physiology to understand the abnormal biological function at the cellular level. Cell therapy is used for the treatment of diseases like cancer by injecting living whole cell or maturation of a specific cell population in a patient.
DNA damage is a cause of Cancer. DNA can be damaged by replication errors, x-rays and certain chemicals. As mutation accumulates over the lifetime of a cell it changes its traits and after the accumulation of a certain set of hallmarks or traits, the cell can become cancerous. Based on the decades of researches and evidence based analyses Scientists has identified 6 hallmark features responsible for the separation of tumour cell from its non-malignant counterparts and 2 additional hallmark features and 2 enabling characteristics aid in the carcinogenesis process.
Diabetes mellitus characterized by hyperglycemia is a group of metabolic diseases caused by unbalanced regulation of the signalling cascades that mediates insulin action in the cell, defect of insulin secretion or both.
Alzhemier disease, a most common type of dementia in elderly is a brain disorder characterized by two protein aggregates formation; senile plaques and neurofibrillary tangles; involved in the neuronal degeneration and death.
The second most common neurodegenerative disorder is Parkinson’s disease which remains incurable. The etiology of the disease is still a mystery but many of the proteins associated with the hereditary disease has been identified as neuronal protein alpha-synuclein shown to be actively involved in the pathogenesis of the disease at the cellular level.
Atherosclerosis is one among the leading global cause of death and disability. It is multifocal disease of medium and large size arteries results that results in heart disease and stroke. Atherosclerosis results from the vascular inflammation, endothelial dysfunction, build-up of cholesterol, lipid, calcium and cell debris within the intima of the vessel wall which forms plaques accumulating the inner walls of the arteries and this decrease or block the blood flow to the targeted organ.
Sickle cell anaemia is a hereditary blood disorder in which a different type of metalloprotein haemoglobin finds in the blood of affected individual. It has shown a single point mutation in codon six of the b -globin gene from glutamic acid to valine produces a mutant protein that is insoluble in the red blood cell, and consequently, forms a crystalline structure.
Obesity is a complex multifactorial chronic disease condition where extra body fat storage cause severe health problems like heart diseases, obstructive sleep apnea, osteoarthritis, type 2 diabetes and certain types of cancers, which in turn reduce life expectancy. The common cause of obesity is poor dietary habit, lack of physical work, genetic susceptibility whereas in some cases genes, medications, psychiatric illness and endocrine disorders are the cause.
Molecular diagnosis is a technique used to detect specific sequences in DNA or RNA that may or may not be associated with disease, including single nucleotide polymorphism (SNP), deletions, rearrangements, insertions and others. The technique is used to diagnose and monitor disease, detect risk, and decide which therapies will work best for individual patients.
Gene therapy is a technique of therapeutic delivery of nucleic acid polymers as a drug into the cell of patient’s to treat disease. The polymers are targeted to possibly correct gene mutation.
A substance or a compound has a biological activity if it has direct effects on a living organism. These effects can both be adverse or beneficial depending on the substance, the dose or the bioavailability. Bioactive compounds are experiencing a growing interest in wide range of applications: geo-medicine, plant science, modern pharmacology, agrochemicals, cosmetics, food industry, nano bio-science etc.
Pharmacogenomics is the study of role of genes in person’s response to drugs. It correlates gene expression and drug absorption, distribution, metabolism, elimination and drug receptor target effects with aims to optimize drug therapy.
Epigenomics is a field which is analogous to genomics and proteomics. It is the systematic analysis of the gene expression and the epigenetic modifications on the genetic material of a cell.
Nuclear medicine is a medical speciality that uses small amounts of radioactive material in the diagnosis and treatment of the disease in early stage like heart disease, neurological disorders, several types of cancer and other abnormalities of the body.
Metabolomics is the study of chemical processes involving metabolites and metabolomic analysis accurately determine the changes in molecular profile related to disease, disease progression, genetic modification, therapeutic intervention or environmental variation.
Personalized medicine is a medicinal model that uses patient’s genetic profile to customize decision made to choose the proper medication, therapy and dose in regards to the prevention, diagnosis and treatment of the disease.
Medicinal biotechnology aims to produce pharmaceutical and diagnostic products for the prevention and treatment of human diseases using living cells and cell materials. The areas of application of medicinal biotechnology are genetic testing, drug production, gene therapy and pharmacogenomics.
OMICS International Organises 300+ Conferences Every Year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 400+ Open access journals which contains over 30000 eminent personalities, reputed scientists as editorial board members.
Journal of Molecular and Genetic Medicine is associated with our international conference "International Conference and Exhibition on Molecular Medicine and Diagnostics" (Molecular Medicine-2015) during August 24-26, 2015 in West Drayton, London, UK with a theme "Exploring the current techniques and research in the field of Molecular medicine and Diagnostics". We are particularly interested in research in the areas of Molecular medicine, which strives to promote the understanding of normal body functioning and disease pathogenesis at the molecular level, and to allow researchers and physician-scientists to use that knowledge in the design of specific tools for disease diagnosis, treatment, prognosis, and prevention.
*Unofficial 2014 Impact Factor was established by dividing the number of articles published in 2012 and 2013 with the number of times they are cited in 2014 based on Google search and the Scholar Citation Index database. If ‘X’ is the total number of articles published in 2012 and 2013, and ‘Y’ is the number of times these articles were cited in indexed journals during 2014 than, impact factor = Y/X.