alexa Bioconjugation|OMICS International|Biosensors Journal

Bioconjugation

Biosensors Journal is one among the best scholarly journals on bioconjugation. All published articles are assigned to Digital Object Identifier (DOI) – CrossRef and are freely accessed using Google scholar. The journal is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. Bioconjugation is the chemical strategy that forms a stable covalent link between two biomolecules. Bioconjugation has enabled breakthroughs across many areas of industry and biomedicine. Bioconjugation of nanoparticles combines unique and orthogonal strengths of two leading edge research fields: the specific interactions of individual biological molecules and novel material properties of nanotechnological compounds. One example of bioconjugation is the biotinylation of antibodies for immunochemical applications using two species of activated biotin. In this case, the activated biotin acts as the acyl acceptor and is coupled to the glutamine residues of a monoclonal antibody. Another example for bioconjugation is the modification of proteins is the synthesis of hapten protein conjugates used in competitive-type immunoassays. The most successful bioconjugation protocol examined was the covalent attachment of biotin to the silica surface through a silane coupling agent via O2 plasma treatment, followed by vapor deposition of the silane. This strategy is a simple method which could easily be extended to other sensor structures due to its flexibility and low impact on the device. OMICS Group is built upon the principles of open access and is determined to provide free and unrestricted access of research articles to scientists around the world for the advancement of science and technology. Submitted articles in the Biosensors Journal avail open accessing. OMICS special features include 21 Day rapid review process and an eminent team of 50,000+ editorial board members and 50,000+ Reviewer team. Open Access initiative helps in unlocking the traditional methods of subscription articles and releasing information to tertiary level readers, who normally would not have access to first hand research studies.
 
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Last date updated on June, 2014