A study on electrochemical deposition in a triple-component CoNiFe system from a chloride electrolyte solution with equal concentrations of Co, Ni, and Fe was performed. The concentrations used were 0.48; 0.083; 0.00625 mol/l, and the temperature was 70°Ð¡. The relative content of the components in the film approached the composition of the electrolyte, though the concentration of each component was slightly decreased. The dependence of the composition of films on the current density is explained by concentration polarization.
Abdunnaser Mohamed Etorki, Ezzedein Mohamed Aboushloa*
Nanometer-sized titanium dioxide prepared in the Lab chemically modified with 8-hydroxyquinolin and used for selective solid phase extraction processes, separation and preconcentration process of aluminum (III) from aqueous solutions prior to its determination by Inductively Coupled Plasma optical emission-Mass spectrometry(ICP-MS) and Graphite furnace atomic Absorption Spectrometry(GFAAS). The optimal conditions for the proposed solid phase extraction (SPE: 0,1g of TiO2- modified oxine, 6h shaking time,
pH 6.5). The experimental results was fitted well to Langmuir isotherm equation to determine the maximum adsorption capacity.The static maximum adsorption capacity was 69.013mg/g. The lowest concentration of aluminum (Al+3) was (30.0μg/L) and the highest concentration was (14585μg/L). The method was successfully applied to the determination of trace of aluminum in areas near to the factories in
east of Tripoli.
Venu Sangal *
In this paper the influence of solvent dielectric constant on the rate of oxidation of p-methoxybenzaldehyde and pmethylbenzaldehyde with t-BuOCl has been studied in various solvent mixtures of acetic acid and water. The results indicate that in the oxidation of p-methoxybenzaldehyde with t-BuOCl the rate increases with increase in the percentage of acetic acid (from 10% to 40%), but the rate decreases with further increace in acetic acid content (50-80% HOAc). In the oxidation of p-methylbenzaldehyde with t- BuOCl the rate is maximum at 50% HOAc and decreases on either side of this percentage.
Sujith*, Chudamani B and Subhas S Karki
DOI: 10.37421/2150-3494.2022.13.304
All the compounds (CH-69 to CH-84) were evaluated for their cytostatic activity against human HeLa cervix carcinoma cells, human CEM CD4þ T-lymphocytes as well as murine L1210 cells. All assays were performed in 96 well microtiter plates. To each well were added (5-7.5) × 104 tumor cells and a given amount of the test compound. The cells were allowed to proliferate for 48 h (murine leukemia L1210 cells) or 72 h (human lymphocytic CEM and human cervix carcinoma HeLa cells) at 37°C in a humidified CO2 controlled atmosphere. At the end of the incubation period, the cells were counted in a coulter counter. The IC50 (50% inhibitory concentration) was defined as the concentration of the compound that inhibited cell proliferation by 50%. The cytotoxicity and antiviral activity of a new series of 2-arylimidazo[2,1-b] [1,3,4]thiadiazol-6-yl)-2H-chromen-2-one against different MDCK cell cultures, HeLa cell cultures, vero cell cultures, CRFK cell cultures is reported. Among the tested compounds, inhibitory effects of compounds (CH-69 to CH-84) on the proliferation of murine leukemia cells (L1210) and human T-lymphocyte cells (CEM) and human cervix carcinoma cells (HeLa).
Peter Kenny
Sachin Babar*, S. L. Padwal and P. V. Raut
DOI: 10.37421/ 2150-3494.2022.13.5.290
The present paper reports the simple, rapid, accurate and precise RP-HPLC method for the simultaneous estimation of Perindopril erbumine and Amlodipine besylate in bulk and formulated drug substance. The reverse phase liquid chromatographic analysis has been performed on a Kromasil C8 (4.6 mm × 250 mm, 5 µ particle size) column with mobile phase Buffer (6.8 g Potassium dihydrogen orthophosphate) and Acetonitrile in the ratio 59:41 with adjusted pH 2.6 with orthophosphoric acid and column oven temperature 40°C. The flow rate of mobile phase was adjusted 1.0 ml/min. and the injection volume 10 µl. Detection was performed at 210 nm. The retention time of Perindopril erbumine and Amlodipine Besylate were found to be 4.483 min. and 6.767 min, the linearity was observed in the concentration range from 20% to 160% of nominal concentration of Perindopril erbumine and Amlodipine Besylate correlation coefficient was 0.999 for both drugs. The % recovery was found to be within the limits of the acceptance criteria with average recovery of 99.4% for perindopril erbumine and 99.6% for Amlodipine besylate. The % RSD below 2.0 shows high precision of proposed method.
Deepa Dumbreabd*, Vasant R Choudharya, H Balochb, MTH Siddiquib, N Sabzoib, ML Kantamc, MK Dongred and S Umbarkard
DOI: 10.37421/2150-3494.2022.13.5.290
A highly efficient, solvent-free and versatile greener protocol was developed for the synthesis of coumarins from resorcinol an ethyl acetoacetate via Pechmann condensation using heterogeneous recyclable FeCl3/MCM41 catalyst. This method is simple, cost effective, and benefits from the elimination of waste streams generated with conventional acid catalysts. The influence of catalyst calcination temperature as well as various solvent on conversion and product selectivity has also been studied in this work. The developed FeCl3/ MCM41 catalysts showed excellent catalytic performance with 60%-75% yields for coumarins, depending on the catalyst pretreatment and reaction conditions used. Moreover, FeCl3/MCM41 catalyst treated at 400°C can be reused efficiently for five times without a significant loss of its activity, which was attributed to synergistic effects of metal-support interactions, especially unique acid-redox properties of FeCl3.
Karim Eyubov
The amount, rate of formation and radiation-chemical yields of molecular hydrogen obtained from the process of radiolysis under the influence of gamma quanta (60Co, P=9.276 rad/s, T=300 K) in the nano-SiO2/H2O system with a mass of particle of m=0.2 g and size of silicon particle of d=20÷60 nm by changing of water mass (m=0.01÷0.8 g) were studied. It was found that the rate of formation and radiationchemical yield of molecular hydrogen determined by increasing the mass of water • decrease by 10 times for water, • increase by 8 times for nano-silicon dioxide, • for common system, increase at the values of water mass of 0.01 gm H2O 0.2 g, have the maximum at mH2O =0.2 g and decrease at 0.2 g< mH2O 0.8 g.
DOI: 10.37421/2150-3494.2022.13.313
DOI: 10.37421/2150-3494.2022.13.311
Steel and iron are the most seriously utilized metals because of their reasonableness; nonetheless, they are defenseless to erosion (rust), which is a worldwide pestilence.
DOI: 10.37421/2150-3494.2022.13.310
DOI: 10.37421/2150-3494.2022.13.312
DOI: 10.37421/2150-3494.2022.13.314
AM Elessawy*, AA El-Barbary and Eman A ElBastawissy
DOI: 10.37421/2150-3494.2023.14.329
New bromazepam derivatives namely; 7-bromo-5-(pyridin-2-yl)-1,3-dihydro-2H-benzo[e] [1,4]diazepine -2-thione and 7-bromo-1-(4,6- dichloro-1,3,5-triazin-2-yl)-5-(pyridin-2-yl)-1,3-dihydro-2H-benzo[e] [1,4]diazepin-2-one have been prepared and characterized by spectroscopic methods (FT-IR, 1H-NMR, UV-visible and EI-mass). Furthermore, the fluorometric method has been developed to detect bromazepam in biological fluid. The new methods are based on measuring excitation and emission spectra of the reaction of bromazepam with cyanuric chloride in pyridine solution compared with excitation and emission spectra free bromazepam in methanolic solution.
Kebede Mamo*, Yared Shewarega and Aklilu Melese
DOI: 10.37421/2150-3494.2023.14.330
Aflatoxin producing substances are extremely dangerous to humans and can result in cancer when taken in foods contaminated with aflatoxin. In this study, the levels of aflatoxins (B1, B2, G1, and G2) in samples of maize collected from several Shebelle Zone districts were quantified. It was examined using a fluorescence detector and UHPLC. The extraction solvents (80:20 v/v percent) were methanol and water. Standard solutions of aflatoxins between 0.5 and 7 g/kg (ppb) demonstrated strong linearity from the calibration curve with regression coefficient (R2) values of >0.9989. The spiked sample average percentage recoveries ranged from 89.78 to 97.87 percent. The average total aflatoxin values in the maize samples from K1, K2, and K3 were 0.14, 356.19, and 174.05 g/kg, respectively. Except for K1, all of the investigated maize samples had aflatoxin levels that above the upper tolerance limits established by international agencies like WHO, and the EU.
Effect of metallic deposited nanoparticles on screen printed carbon with tetrathiafulvalene incorporated ink, was tested by three electrochemical procedures. First one electrodeposition at constant potential and two cyclic voltammetry procedures that applied changes in step potential, scan rate and delay time. X-rays Fluorescence (XRF), Scanning Electronic and Atomic Force Microscopy (SEM) and (AFM) respectively were performed and metallic nanoparticles deposits were characterized through their SEM images. XRF provide metal percentage deposited by electrochemical procedures. AFM parameters let to know electrodes modi ied surface characteristics. Nanoparticles electrochemically deposited electrodes were modi ied with superoxide dismutase enzyme and tested on epinephrine biosensor amperometric calibration curves. Platinum Nanoparticles (PtNPs) modi ied electrodes nature surpasses AFM surface parameters. There is correlation between low AFM parameters and high slope epinephrine calibration curve excepting PtNPs case. Nanoparticles of platinum deposited by cyclic voltammetry procedure 1 showed higher epinephrine slope calibration curve than the others nanoparticles deposited by constant potential and cyclic voltammetry procedure. Higher linearity and stability was showed for PtNPs performed cyclic voltametry procedure; this one was selected to validation of biosensor. Developed biosensor showed reproducibility of 2.9% and detection limit of 22.8 μm. Biosensor analysis of epinephrine pharmaceutical injection was 103.1% with RSD 5.4%.
Mohitha Pushparaj, Kizhaeral S. Subramanyam* and Raveendran Muthurajan
DOI: 10.37421/2150-3494.2023.14.374
Rice is a staple food for more than 50% of the global population and there is close relationship between rice eaters and the prevalence of diabetes. Among the landraces, ‘Kavuni’ is considered as a traditional brownish black variety which is extensively cultivated in the southern part of India, Tamil Nadu. The Tamil Nadu Agricultural University is among the first State Agricultural University to release therapeutic rice in 2023 as Co.57. This study aimed to identify and quantify the major anti-diabetic compounds present in Kavuni rice grain extracted using various solvents. Metabolite profiling using LC-QTOF-MS analysis has revealed that 31 phytochemicals detected among them anthocyanins and flavonoids are predominant. Ethanolic extract of Kavuni rice grain had the highest concentration of anthocyanins, cyanidin 3-O-glucoside (61.31 ± 0.04 mg/g). The highest antioxidant activities in the ethanolic extract of Kavuni rice were detected as 89.51 ± 0.1% and 82.97 ± 0.09% measured using anti-oxidant assays. Further, Kavuni rice had the highest inhibition of carbohydrate digestive enzymes (α-amylase and α-glucosidase) 82.30% and 70.21%, respectively. The data clearly demonstrated that land race “Kavuni” carries phytochemicals that are known to regular postprandial hyperglycemia by inhibiting anti-diabetic enzyme could lower the risk of developing Type-2 diabetes.
Abi Legesse* and Addis Ababa
This research was carried out to investigate the physicochemical parameters of livestock drinking water samples collected from Falfal, Degehabur and Bulale areas in Somali regional state of Ethiopia. The objective of this research was to analyze the physicochemical parameters of water ponds used for livestock drink. The result was recorded that, the pH, Temperature, Total Dissolved Solid and Total hardness was 7.17°C ± 0.03°C, 22.51°C ± 0.18°C, 17.50 ± 2.60 mg/L and 825.22 ± 92.18 mg/L, respectively. The mean concentration of Chloride ion, Magnesium ion and calcium ion was 422.09 ± 64.05 mg/L, 61.37 ± 6.56 mg/L, and 200.70 13.23 mg/L, respectively. The mean Chemical Oxygen Demand and Biological Oxygen Demand were also recorded which was 12.67 0.54 mg/L and 7.47 0.67 mg/L, respectively.
The obtained results were also compared to the national and international standards to determine the quality of livestock drinking water. Accordingly, the measured pH was in agreement with World health organization and Ethiopian standards agency standards, which was 6.5 to 8.5. The Temperature, Total hardness and chloride ion concentration was above the standard limit set by World health organization and Ethiopian standards agency. The concentration of Total Dissolved Solid, Mg2+ and Ca2+ was in agreement with World health organization and Ethiopian standards agency standards. The standards for Chemical Oxygen Demand and Biological Oxygen Demand were not available both from World health organization and Ethiopian standards agency.
Chemical Sciences Journal received 912 citations as per Google Scholar report
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