Oral Health and Dental Management

Abstract

Solitary Plasmacytoma in Mandible with 7 Year Follow up Data

Balreddy P, Prashanth Panta, Sridhar Reddy, Sandhya Gokavarapu

Solitary plasmacytoma is a plasma cell dyscrasia that rarely involves the jaws. Most of the solitary plasmacytomas progress into multiple myelomas over a period of 3-4 years. Although they are similar to multiple myeloma, these lesions must be differentiated from multiple myeloma as prognosis between the both varies considerably. Plasmacytoma is benign and does not require aggressive therapy. Multiple myeloma on the other hand are associated with poor prognosis and systemic involvement. This report describes a plasmacytoma in the mandible of a middle aged Indian patient. He was treated by radiotherapy at a regional cancer center and reported to us after 7 years from the date of initial presentation. To our surprise, even several years after radiotherapy, he did not develop multiple myeloma. We present a discussion on plasmacytoma, its relationship to multiple myeloma, prognosis and current therapies.