GET THE APP

..

Chemical Sciences Journal

ISSN: 2150-3494

Open Access

Synthesis and Biological Evaluation of 2-Aryl - 6, 7-Difluorophenyl-1,3,4- Oxadiazolo (3,2-a) (1,3,5)-Triazine-5-(6H,7H)-Thiones

Abstract

Kiran Mishra

2-Aryl-6,7-difluorofenyl-1,3,4-oxadiazolo (3,2-a) (1,3,5)- triazine-5-(6H,7H)- thiones (2a-j) have been orchestrated by the cyclo expansion of para-fluorophenyl 4 –fluoro phenyl isothiocynate and 2-(4-fluorobenzylidine) to (1a-j) 2-amino - 5-phenyl-1,3,4-oxadiazole in dry toluene all the integrated compounds were very much described by their elemental analysis and spectral data. The integrated compounds have been screened for their antifungal action against Phytophthora infestans and Colletotrichum falcatum. Results demonstrated that greatest antifungal activity was appeared by the compounds 2b, 2c, 2g and 2h. These compounds demonstrated 99%, 98%, 99% and 97% hindrance of Phytophthora infestans and 97%, 96%, 98% and 97% Colletotrichum falcatum at 1000 ppm respectively.

PDF

Share this article

Google Scholar citation report
Citations: 912

Chemical Sciences Journal received 912 citations as per Google Scholar report

Chemical Sciences Journal peer review process verified at publons

Indexed In

 
arrow_upward arrow_upward