|"Journal of Psychiatry is one of the Best Journals in Posttraumatic Stress Disorder. Journal of Psychiatry is an international, non-profit, professional association organized to develop and promote comprehensive, clinically effective and empirically based resources and responses to trauma and dissociation and to address its relevance to other theoretical constructs. We also provide many author benefits, such as free PDFs, a liberal copyright policy. Posttraumatic Stress Disorder (PTSD) is a prevalent, chronic, and disabling anxiety disorder that may develop following exposure to a traumatic event. The majority of individuals with Posttraumatic Stress Disorder often have comorbid psychiatric conditions such as major depression, generalized anxiety disorder, and substance use disorders, and are at increased risk for suicide. Despite the public health significance of Posttraumatic Stress Disorder relatively little is known about the etiology or pathophysiology of this disorder, and pharmacotherapy development to date has been largely opportunistic instead of mechanismbased. One promising target for modulation is Tropomyosin Receptor Kinase B (TrkB), the receptor for Brain-Derived Neurotrophic Factor (BDNF), a signaling pathway important for neuronal plasticity, survival, and growth. âAlexander Neumeister, The Role of BDNF-TrkB Signaling in the Pathogenesis of PTSDâ
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